
Although not all of these side effects may occur, if they do occur they may need medical attention.Ĭheck with your doctor immediately if any of the following side effects occur while taking warfarin: Less common Serious side effects of CoumadinĪlong with its needed effects, warfarin (the active ingredient contained in Coumadin) may cause some unwanted effects. Instruct patients about prevention measures to minimize risk of bleeding and to report signs and symptoms of bleeding. Drugs, dietary changes, and other factors affect INR levels achieved with warfarin sodium therapy. Regular monitoring of INR should be performed on all treated patients. Taking melatonin with these drugs might increase the risk of seizures.Warfarin can cause major or fatal bleeding. Melatonin can stimulate immune function and interfere with immunosuppressive therapy. This medication used to treat obsessive-compulsive disorder can increase melatonin levels, causing unwanted excessive drowsiness. Use melatonin cautiously if you take drugs such as diazepam (Valium, Valtoco, others) and others that are affected by these enzymes.

Research suggests that melatonin might slightly reduce the time it takes to fall asleep, but its effects on sleep quality and total sleep time aren't clear.

Research shows that melatonin reduces the length of time needed to fall asleep and advances the start of sleep in adults and children with this condition. In this disorder, your sleep pattern is delayed two hours or more from a conventional sleep pattern, causing you to go to sleep later and wake up later. Delayed sleep phase (delayed sleep-wake phase sleep disorder).Melatonin can help improve these disorders in adults and children. Circadian rhythm sleep disorders in the blind.Research on melatonin use for specific conditions shows:
